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Bio/BiochemQuestion 5 of 13 in Bio/Biochem

MCAT Bio/Biochem practice questionDigestive system

A patient presents with chronic digestive issues, including irregular bowel movements and impaired nutrient absorption, despite no apparent damage to the brain or spinal cord. This suggests a localized problem within the intrinsic neural control of the gastrointestinal tract. Which of the following statements best describes a key feature of the enteric nervous system that allows it to function largely independently of the central nervous system?

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The answer

Correct answer: D. It possesses complete reflex arcs, enabling it to coordinate digestive processes without direct CNS input.

Tested concept: Enteric nervous system

Explanation

The enteric nervous system (ENS) is often referred to as the 'brain of the gut' because it contains its own complete reflex arcs, including sensory neurons, interneurons, and motor neurons. This intrinsic neural network allows the ENS to autonomously control and coordinate complex digestive functions, such as peristalsis and glandular secretions, even in the absence of direct input from the central nervous system (CNS). While the CNS can modulate ENS activity, the ENS's ability to operate independently is due to these self-contained reflex pathways. Distractor 1 is incorrect because while the parasympathetic nervous system does influence the ENS, the ENS itself has intrinsic activity and can function without constant direct CNS input. It is not solely reliant on parasympathetic innervation for all regulation. Distractor 2 is incorrect because while the ENS does send sensory information to the CNS, its primary characteristic for independence is its ability to initiate and coordinate motor and secretory functions locally, not just to report to the brain for conscious perception. Distractor 3 is incorrect because the ENS utilizes a wide variety of neurotransmitters, including acetylcholine, norepinephrine, serotonin, ATP, and nitric oxide, among others, to regulate gastrointestinal function, not exclusively acetylcholine.

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